01 / DESIGN
What was studied?
Residual artery segments from surgery were studied as isolated rings, with endothelial removal and nitric-oxide-pathway inhibition.
02 / FINDINGS
What did the researchers report?
BPC-157 altered contractile responses, with stronger relaxation in rings retaining an intact endothelium.
03 / LIMITS
How should it be interpreted?
Human tissue origin does not mean patients were treated. Isolated-vessel concentration responses cannot establish systemic cardiovascular benefit, exposure or safety.
Loti Labs Peptide editorial reading note. Based on the linked source record. Methods and corrections.