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Endocrine research

Kisspeptin-10 during ewe puberty: following endogenous changes

Ewe lambs were repeatedly sampled across development to compare circulating neuropeptides with the timing of first ovulation.

Preclinical studyPaper year: 2026Kisspeptin-10

01 / DESIGN

What was studied?

Ewe lambs were repeatedly sampled across development to compare circulating neuropeptides with the timing of first ovulation.

02 / FINDINGS

What did the researchers report?

Kisspeptin-10 and neurokinin B rose with age, while dynorphin-related patterns moved in the opposite direction across the studied groups.

03 / LIMITS

How should it be interpreted?

These are developmental associations rather than a treatment experiment. Pregnancy grouping, age and species-specific physiology limit causal and human interpretation.

Loti Labs Peptide editorial reading note. Based on the linked source record. Methods and corrections.

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