01 / DESIGN
What was studied?
A pilot study measured MOTS-c in serum, urine and dialysate from thirty-two stable peritoneal-dialysis patients.
02 / FINDINGS
What did the researchers report?
Associations differed by compartment. Urinary levels correlated with both lower oxidative-stress markers and greater arterial stiffness, while dialysate levels showed a different vascular pattern.
03 / LIMITS
How should it be interpreted?
Small observational correlations do not identify cause or indicate that supplementation helps. Renal handling and sampling compartment are important alternative explanations.
Loti Labs Peptide editorial reading note. Based on the linked source record. Methods and corrections.