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Cell & tissue research

Oral glutathione and body stores: biomarkers from a six-month trial

A controlled study measured glutathione in several body compartments rather than disease outcomes.

Clinical trialPaper year: 2015Glutathione

01 / DESIGN

What was studied?

A randomized, double-blind, placebo-controlled trial followed 54 nonsmoking adults for six months. It investigated oral glutathione supplementation and measured glutathione in blood-related compartments and exfoliated mouth cells.

02 / FINDINGS

What did the researchers report?

The investigators reported increases in glutathione stores in several measured compartments during supplementation. Some changes varied by time, compartment and group. A subset of participants was also evaluated for immune-related markers.

03 / LIMITS

How should it be interpreted?

An increase in a biomarker does not by itself demonstrate prevention or treatment of disease. This was oral supplementation, not an investigation of catalog vials or another administration route. The sample size and selected healthy population also limit broader conclusions.

Loti Labs Peptide editorial reading note. Based on the linked source record. Methods and corrections.

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